Now enrolling pediatric and teen participants ages 2 and up!
Revealing connections between inflammation, chronic medical conditions, and mental health.
An easy-to-use, online health platform—accessible via web or app—designed to bring patients, their healthcare providers, and researchers together.
Your voice. Your platform. Let's unhide, together.
Welcome to unhide®
Brain inflammation (or neuroinflammation), as a result of autoimmune disease, infection, allergy, or injury, can trigger symptoms such as severe fatigue, depression, anxiety, sleep trouble, brain fog, confusion, and mood changes. These symptoms can be misleading due to a lack of clear diagnostic methods or established standards of care. Evidence is pointing to inflammation as a potential missing link, hidden in plain sight.
unhide® was created by the Brain Inflammation Collaborative to uncover hidden connections between seemingly unrelated symptoms and diagnoses, and to advance patient-centered research that drives better diagnosis and treatment. In 2025, the Brain Inflammation Collaborative joined forces with Solve M.E., an organization with a long history of supporting patients, to combine unhide® with Solve Together, uniting efforts to reach more patients, support our communities, and push forward progress toward long-overdue answers.
unhide® is a digital health platform developed in collaboration with patient experts, researchers, and clinicians. It brings together data from symptom tracking, wearable devices, health history, and validated survey instruments to support patients and help researchers achieve their goals.
Ready to uncover more?
unhide® enables patients and caregivers to track symptoms, identify patterns, and visualize their symptoms over time. Our patient community’s powerful, real-world data will be used to seek better diagnostics, treatments, and cures for ME/CFS, Long Covid, and other chronic conditions associated with brain inflammation. Participants can also choose to be contacted and recruited for clinical trials or research studies.
Our approach complements the work of single-condition advocacy groups by fostering a collective research framework that spans 30+ related diseases. Through our digital health platform, patients from diverse backgrounds can contribute valuable data, allowing for large-scale, cross-disease comparisons that traditional studies often lack.
The Mental Health Connection
The connections between brain inflammation and mental health symptoms can be difficult to pinpoint and are often missed in regular clinical assessments.
As part of our research, we aim to identify ways to determine relationships between brain inflammation and mental health symptoms such as brain fog, difficulty concentrating, memory issues, sleep problems, mood changes, anxiety, and depression.
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unhide® is powered by the Brain Inflammation Collaborative
Our mission is to revolutionize the diagnosis and treatment of brain inflammation related diseases through coordinated research that connects patients and researchers through centralized patient data.
Our Collaborators
