Email Signup | unhide®

Here are the next steps if you qualify for registration:

Step 1

You will receive an email with important information from our clinical trial platform. (If you haven’t received the email within 7 days, please check your SPAM folder for a message from webmaster@clsds.com.)

Step 2

This email will contain:

Your 6-digit Subject PIN (passcode) that you can use to log into the Unhide ™ platform
Your Subject ID
Additional instructions on participation

Step 3

Please write down your PIN and Subject ID in a safe place so you can refer back to it throughout your participation!

Step 4

When you log into the Unhide ™ Platform, you will be prompted to agree to the Informed Consent form, which will provide detailed study information.

Please review all the study details before agreeing to participate in this study.

Step 5

If you are enrolling on behalf of a participant aged 7-17, please ensure they are present when the form is reviewed and additional assent is given.

Mental Health Connection

Understanding brain inflammation and mental health symptoms can be difficult and confusing to families, clinicians – and even researchers. As part of our research, we hope to identify ways to determine when brain inflammation is involved in the triggering of mental health symptoms. Did you know brain inflammation and mental health symptoms can result post-viral or even from bacteria from an abscessed tooth or strep infection? And some autoimmune illnesses such as rheumatoid arthritis and POTS are now thought to have associations with brain inflammation. Even long COVID is being studied for the connection to brain inflammation and mental health symptoms. Help us to collect the data and the bio-samples we need to find the answers to better understand the connection between brain inflammation and mental health. Some of the mental health symptoms we are investigating:

Behavior changes
OCD
Abnormal restrictive eating behaviors
Depression
Anxiety disorders
Seizures

Brain fog or cognitive issues
Intrusive thoughts
Chronic fatigue
Motor and vocal tics
Light-headedness and/or dizziness
Joint or nerve pain

See our FAQ’s on Eligibility. Learn more about brain inflammation and mental health on our sponsor website – the Brain Information Collaborative – a larger more extensive site coming soon!

Bio-Samples

Participants may be asked to voluntarily provide a non-invasive biological sample, such as urine or saliva, to be analyzed by our researchers. These samples will be taken to correspond with certain life events such as initial diagnosis, illness flares, hospitalization, or other notable life events the patient may experience. Tying these symptoms and life events to real-time patient bio-samples will help to provide researchers with a clearer picture needed to decode the mystery of the effects of brain inflammation on mental and physical health. We are also seeking healthy individuals willing to participate as healthy controls. To complete clinical research, results from healthy controls are compared to results from the group being studied. Patients could also be asked to voluntarily provide bio-samples for outside medical testing services such as Moleculera Labs, SomaLogic, or the BioBank of the Americas to become part of a larger study to learn more about a variety of immune markers such as cytokines or antibodies, proteomics or genetics in neuroinflammatory illnesses. Learn more about how to make a difference in our FAQ’s .

The Project

The Unhide™ Project is a simple to use, online digital platform that easily tracks patient health stories, symptoms, life events, and bio-samples all in one place. With this data, we look to further the advancements in diagnosis, treatment and prevention of brain inflammation through this clinical research registry and biobank platform.

Our goal is to look for patterns and triggers in both mental and physical health. But we also hope this tool will help families ease their overall burden of collecting and organizing patient health care data – for themselves and for the ease of sharing with healthcare providers.

The beginning phase of our ongoing research study will include those with a diagnosis or suspected diagnosis of one or more of the following:

Autoimmune forms of arthritis (e.g. Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis)
Autoimmune Encephalitis
Celiac Disease
Ehlers Danlos Syndrome (EDS)
Inflammatory Bowel Disease (IBD, Crohn’s Disease & Ulcerative Colitis)
Lupus (any type)
Mast Cell Activation Syndrome (MCAS)
ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome)
PANDAS (Pediatric Acute-Onset Neuropsychiatric Disorder Associated with Strep)
PANS (Pediatric Acute-Onset Neuropsychiatric Syndrome)
Post-COVID syndromes marked by exacerbation or onset of at least one mental health or neurological symptom (including difficulties with thinking or memory
POTS (Postural Orthostatic Tachycardia Syndrome)
Psoriasis
Sjogren’s Syndrome
Traumatic Brain Injury
Tourette’s
Bipolar Disorder (enrolled by clinicians only)
Eating disorders involving restrictive eating and/or purging (Anorexia Nervosa, Bulimia Nervosa, ARFID
Major Depression
Narcolepsy
Obsessive Compulsive Disorder (OCD) and/or other anxiety disorders (exclusive of simple phobias)
Post-Traumatic Stress Disorder (PTSD)

By participating in the Unhide™ Project, you will join a larger collaborative effort to help us learn about mental health symptoms that we feel are driven by brain inflammation. Keep checking back as additional diseases and illnesses get added to our research scope.

Read our FAQ’s to learn more about eligibility and benefits of joining our project.